Cargando…

The Glycolysis Inhibitor 2-Deoxy-d-Glucose Exerts Different Neuronal Effects at Circuit and Cellular Levels, Partially Reverses Behavioral Alterations and does not Prevent NADPH Diaphorase Activity Reduction in the Intrahippocampal Kainic Acid Model of Temporal Lobe Epilepsy

Temporal lobe epilepsy is the most drug-resistant type with the highest incidence among the other focal epilepsies. Metabolic manipulations are of great interest among others, glycolysis inhibitors like 2-deoxy d-glucose (2-DG) being the most promising intervention. Here, we sought to investigate th...

Descripción completa

Detalles Bibliográficos
Autores principales: Khatibi, Vahid Ahli, Rahdar, Mona, Rezaei, Mahmoud, Davoudi, Shima, Nazari, Milad, Mohammadi, Mohammad, Raoufy, Mohammad Reza, Mirnajafi-Zadeh, Javad, Hosseinmardi, Narges, Behzadi, Gila, Janahmadi, Mahyar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444119/
https://www.ncbi.nlm.nih.gov/pubmed/36064822
http://dx.doi.org/10.1007/s11064-022-03740-8