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Prediction of histone post-translational modification patterns based on nascent transcription data

The role of histone modifications in transcription remains incompletely understood. Here we examine the relationship between histone modifications and transcription using experimental perturbations combined with sensitive machine-learning tools. Transcription predicted the variation in active histon...

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Detalles Bibliográficos
Autores principales: Wang, Zhong, Chivu, Alexandra G., Choate, Lauren A., Rice, Edward J., Miller, Donald C., Chu, Tinyi, Chou, Shao-Pei, Kingsley, Nicole B., Petersen, Jessica L., Finno, Carrie J., Bellone, Rebecca R., Antczak, Douglas F., Lis, John T., Danko, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444190/
https://www.ncbi.nlm.nih.gov/pubmed/35273399
http://dx.doi.org/10.1038/s41588-022-01026-x