Evaluation of Physicochemical Properties, Pharmacokinetics, Biodistribution, Toxicity, and Contrast-Enhanced Cancer MRI of a Cancer-Targeting Contrast Agent, MT218

Preclinical assessments were performed according to the US Food and Drug Administration guidelines to determine the physicochemical properties, pharmacokinetics, clearance, safety, and tumor-specific magnetic resonance (MR) imaging of MT218, a peptidic gadolinium-based MR imaging agent targeting to...

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Detalles Bibliográficos
Autores principales: Li, Yajuan, Gao, Songqi, Jiang, Hongfa, Ayat, Nadia, Laney, Victoria, Nicolescu, Calin, Sun, Wenyu, Tweedle, Michael F., Lu, Zheng-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Special Issue 2022-Contrast Media
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444296/
https://www.ncbi.nlm.nih.gov/pubmed/35703463
http://dx.doi.org/10.1097/RLI.0000000000000881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444296/
https://www.ncbi.nlm.nih.gov/pubmed/35703463
http://dx.doi.org/10.1097/RLI.0000000000000881

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