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Inhibition of Bruton's Tyrosine Kinase Alleviates Monocrotaline-Induced Pulmonary Arterial Hypertension by Modulating Macrophage Polarization

Macrophage accumulation and activation contribute to the development of pulmonary arterial hypertension (PAH), while Bruton's tyrosine kinase (BTK) is an important regulator for the activation and polarization of macrophage. However, the role of BTK in PAH remains unknown. In the present study,...

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Detalles Bibliográficos
Autores principales: Yu, Min, Wu, Xuecheng, Peng, Liyao, Yang, Mingxia, Zhou, Hong, Xu, Jian, Wang, Jingjing, Wang, Hong, Xie, Weiping, Kong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444460/
https://www.ncbi.nlm.nih.gov/pubmed/36071873
http://dx.doi.org/10.1155/2022/6526036