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Inhibition of Bruton's Tyrosine Kinase Alleviates Monocrotaline-Induced Pulmonary Arterial Hypertension by Modulating Macrophage Polarization
Macrophage accumulation and activation contribute to the development of pulmonary arterial hypertension (PAH), while Bruton's tyrosine kinase (BTK) is an important regulator for the activation and polarization of macrophage. However, the role of BTK in PAH remains unknown. In the present study,...
Autores principales: | Yu, Min, Wu, Xuecheng, Peng, Liyao, Yang, Mingxia, Zhou, Hong, Xu, Jian, Wang, Jingjing, Wang, Hong, Xie, Weiping, Kong, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444460/ https://www.ncbi.nlm.nih.gov/pubmed/36071873 http://dx.doi.org/10.1155/2022/6526036 |
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