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CXCL1-Triggered PAD4 Cytoplasmic Translocation Enhances Neutrophil Adhesion through Citrullination of PDIA1

Aims: Vascular inflammation is critical for the development and progression of atherosclerosis. Previously, we reported that neutrophils adhere to the vascular endothelium in low-density lipoprotein receptor null mice fed a high-fat diet through hypercitrullination of histone H3 by peptidylarginine...

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Detalles Bibliográficos
Autores principales: Aoyama, Jiro, Osaka, Mizuko, Deushi, Michiyo, Hosoya, Shoichi, Ishigami, Akihito, Maehara, Taketoshi, Yoshida, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444809/
https://www.ncbi.nlm.nih.gov/pubmed/34880166
http://dx.doi.org/10.5551/jat.63237