HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection

The hypoxia-inducible factors (HIFs) regulate the main transcriptional pathway of response to hypoxia in T cells and are negatively regulated by von Hippel-Lindau factor (VHL). But the role of HIFs in the regulation of CD4 T cell responses during infection with M. tuberculosis isn’t well understood....

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Detalles Bibliográficos
Autores principales: Liu, Ruining, Muliadi, Victoria, Mou, Wenjun, Li, Hanxiong, Yuan, Juan, Holmberg, Johan, Chambers, Benedict J., Ullah, Nadeem, Wurth, Jakob, Alzrigat, Mohammad, Schlisio, Susanne, Carow, Berit, Larsson, Lars Gunnar, Rottenberg, Martin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445005/
https://www.ncbi.nlm.nih.gov/pubmed/36064840
http://dx.doi.org/10.1038/s41467-022-32639-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445005/
https://www.ncbi.nlm.nih.gov/pubmed/36064840
http://dx.doi.org/10.1038/s41467-022-32639-9

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