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HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection
The hypoxia-inducible factors (HIFs) regulate the main transcriptional pathway of response to hypoxia in T cells and are negatively regulated by von Hippel-Lindau factor (VHL). But the role of HIFs in the regulation of CD4 T cell responses during infection with M. tuberculosis isn’t well understood....
Autores principales: | Liu, Ruining, Muliadi, Victoria, Mou, Wenjun, Li, Hanxiong, Yuan, Juan, Holmberg, Johan, Chambers, Benedict J., Ullah, Nadeem, Wurth, Jakob, Alzrigat, Mohammad, Schlisio, Susanne, Carow, Berit, Larsson, Lars Gunnar, Rottenberg, Martin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445005/ https://www.ncbi.nlm.nih.gov/pubmed/36064840 http://dx.doi.org/10.1038/s41467-022-32639-9 |
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