Cargando…

Development of a red fluorescent protein-based cGMP indicator applicable for live-cell imaging

Cyclic guanosine 3′, 5′-monophosphate (cGMP) is a second messenger that regulates a variety of physiological processes. Here, we develop a red fluorescent protein-based cGMP indicator, “Red cGull”. The fluorescence intensity of Red cGull increase more than sixfold in response to cGMP. The features o...

Descripción completa

Detalles Bibliográficos
Autores principales: Takizawa, Mai, Osuga, Yuri, Ishida, Rika, Mita, Marie, Harada, Kazuki, Ueda, Hiroshi, Kitaguchi, Tetsuya, Tsuboi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445041/
https://www.ncbi.nlm.nih.gov/pubmed/36064581
http://dx.doi.org/10.1038/s42003-022-03790-2