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Combining donor-derived cell-free DNA and donor specific antibody testing as non-invasive biomarkers for rejection in kidney transplantation

Donor specific anti-HLA antibodies (DSA) and donor-derived cell-free DNA (dd-cfDNA) have lead to substantial progress in the non-invasive monitoring of the renal allograft by being able to detect or rule out subclinical rejection and guide immunosuppressive changes. In this study we sought to analyz...

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Detalles Bibliográficos
Autores principales: Obrișcă, Bogdan, Butiu, Maria, Sibulesky, Lena, Bakthavatsalam, Ramasamy, Smith, Kelly D., Gimferrer, Idoia, Warner, Paul, Ismail, Gener, Leca, Nicolae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445050/
https://www.ncbi.nlm.nih.gov/pubmed/36064740
http://dx.doi.org/10.1038/s41598-022-19017-7