Inhibition of mTOR in bovine monocyte derived macrophages and dendritic cells provides a potential mechanism for postpartum immune dysfunction in dairy cows

Dairy cattle experience a profound nutrient deficit postpartum that is associated with immune dysfunction characterized by heightened inflammation and reduced pathogen clearance. The activation of the central nutrient-sensing mTOR pathway is comparatively reduced in leukocytes of early postpartum da...

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Detalles Bibliográficos
Autores principales: Sipka, Anja S., Chandler, Tawny L., Weichhart, Thomas, Schuberth, Hans-Joachim, Mann, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445052/
https://www.ncbi.nlm.nih.gov/pubmed/36064574
http://dx.doi.org/10.1038/s41598-022-19295-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445052/
https://www.ncbi.nlm.nih.gov/pubmed/36064574
http://dx.doi.org/10.1038/s41598-022-19295-1

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