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CPEB2 m6A methylation regulates blood–tumor barrier permeability by regulating splicing factor SRSF5 stability
The blood–tumor barrier (BTB) contributes to poor therapeutic efficacy by limiting drug uptake; therefore, elevating BTB permeability is essential for glioma treatment. Here, we prepared astrocyte microvascular endothelial cells (ECs) and glioma microvascular ECs (GECs) as in vitro blood–brain barri...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445078/ https://www.ncbi.nlm.nih.gov/pubmed/36064747 http://dx.doi.org/10.1038/s42003-022-03878-9 |