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CPEB2 m6A methylation regulates blood–tumor barrier permeability by regulating splicing factor SRSF5 stability

The blood–tumor barrier (BTB) contributes to poor therapeutic efficacy by limiting drug uptake; therefore, elevating BTB permeability is essential for glioma treatment. Here, we prepared astrocyte microvascular endothelial cells (ECs) and glioma microvascular ECs (GECs) as in vitro blood–brain barri...

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Detalles Bibliográficos
Autores principales:	Zhang, Mengyang, Yang, Chunqing, Ruan, Xuelei, Liu, Xiaobai, Wang, Di, Liu, Libo, Shao, Lianqi, Wang, Ping, Dong, Weiwei, Xue, Yixue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445078/ https://www.ncbi.nlm.nih.gov/pubmed/36064747 http://dx.doi.org/10.1038/s42003-022-03878-9

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