Cargando…

Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats

Oxytocin is involved in pain transmission, although the detailed mechanism is not fully understood. Here, we generate a transgenic rat line that expresses human muscarinic acetylcholine receptors (hM3Dq) and mCherry in oxytocin neurons. We report that clozapine-N-oxide (CNO) treatment of our oxytoci...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishimura, Haruki, Yoshimura, Mitsuhiro, Shimizu, Makiko, Sanada, Kenya, Sonoda, Satomi, Nishimura, Kazuaki, Baba, Kazuhiko, Ikeda, Naofumi, Motojima, Yasuhito, Maruyama, Takashi, Nonaka, Yuki, Baba, Ryoko, Onaka, Tatsushi, Horishita, Takafumi, Morimoto, Hiroyuki, Yoshida, Yasuhiro, Kawasaki, Makoto, Sakai, Akinori, Muratani, Masafumi, Conway-Campbell, Becky, Lightman, Stafford, Ueta, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445084/
https://www.ncbi.nlm.nih.gov/pubmed/36064593
http://dx.doi.org/10.1038/s42003-022-03879-8