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Astrogliosis in aging and Parkinson’s disease dementia: a new clinical study with (11)C-BU99008 PET

The role of astrogliosis in the pathology of brain aging and neurodegenerative diseases has recently drawn great attention. Imidazoline-2 binding sites represent a possible target to map the distribution of reactive astrocytes. In this study, we use (11)C-BU99008, an imidazoline-2 binding sites-spec...

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Detalles Bibliográficos
Autores principales: Mohamed, Mohamed A, Zeng, Zhou, Gennaro, Marta, Lao-Kaim, Nicholas P, Myers, Jim F M, Calsolaro, Valeria, Femminella, Grazia Daniela, Tyacke, Robin J, Martin-Bastida, Antonio, Gunn, Roger N, Nutt, David J, Edison, Paul, Piccini, Paola, Roussakis, Andreas-Antonios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445175/
https://www.ncbi.nlm.nih.gov/pubmed/36072646
http://dx.doi.org/10.1093/braincomms/fcac199