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CDK9 binds and activates SGK3 to promote cardiac repair after injury via the GSK-3β/β-catenin pathway

The mammalian heart possesses entire regeneration capacity after birth, which is lost in adulthood. The role of the kinase network in myocardial regeneration remains largely elusive. SGK3 (threonine-protein kinase 3) is a functional kinase we identified previously with the capacity to promote cardio...

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Detalles Bibliográficos
Autores principales: Sun, Jiateng, Yang, Tongtong, Wei, Tianwen, Zhou, Liuhua, Shan, Tiankai, Chen, Jiawen, Gu, Lingfeng, Chen, Bingrui, Liu, Liu, Jiang, Qiqi, Du, Chong, Ma, Yao, Wang, Hao, Chen, Feng, Guo, Xuejiang, Ji, Yong, Wang, Liansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445272/
https://www.ncbi.nlm.nih.gov/pubmed/36082129
http://dx.doi.org/10.3389/fcvm.2022.970745