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Activation of the NFκB signaling pathway in IL6+CSF3+ vascular endothelial cells promotes the formation of keloids

Background: Keloid is a disease caused by abnormal proliferation of skin fibres, the causative mechanism of which remains unclear. Method: In this study, endothelial cells of keloids were studied using scRNAseq combined with bulk-RNAseq data from keloids. The master regulators driving keloid develop...

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Detalles Bibliográficos
Autores principales: Liu, Delin, Zhang, Yidi, Zhen, Lisha, Xu, Rong, Ji, Zhenling, Ye, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445273/
https://www.ncbi.nlm.nih.gov/pubmed/36082167
http://dx.doi.org/10.3389/fbioe.2022.917726