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Transcriptional bursts and heterogeneity among cardiomyocytes in hypertrophic cardiomyopathy

Transcriptional bursting is a common expression mode for most genes where independent transcription of alleles leads to different ratios of allelic mRNA from cell to cell. Here we investigated burst-like transcription and its consequences in cardiac tissue from Hypertrophic Cardiomyopathy (HCM) pati...

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Detalles Bibliográficos
Autores principales: Burkart, Valentin, Kowalski, Kathrin, Aldag-Niebling, David, Beck, Julia, Frick, Dirk Alexander, Holler, Tim, Radocaj, Ante, Piep, Birgit, Zeug, Andre, Hilfiker-Kleiner, Denise, dos Remedios, Cristobal G., van der Velden, Jolanda, Montag, Judith, Kraft, Theresia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445301/
https://www.ncbi.nlm.nih.gov/pubmed/36082122
http://dx.doi.org/10.3389/fcvm.2022.987889