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Cyclic di-AMP as endogenous adjuvant enhanced BCG-induced trained immunity and protection against Mycobacterium tuberculosis in mice

Bacillus Calmette-Guérin (BCG) is a licensed prophylactic vaccine against tuberculosis (TB). Current TB vaccine efforts focus on improving BCG effects through recombination or genetic attenuation and/or boost with different vaccines. Recent years, it was revealed that BCG could elicit non-specific h...

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Detalles Bibliográficos
Autores principales: Ning, Huanhuan, Kang, Jian, Lu, Yanzhi, Liang, Xuan, Zhou, Jie, Ren, Rui, Zhou, Shan, Zhao, Yong, Xie, Yanling, Bai, Lu, Zhang, Linna, Kang, Yali, Gao, Xiaojing, Xu, Mingze, Ma, Yanling, Zhang, Fanglin, Bai, Yinlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9445367/
https://www.ncbi.nlm.nih.gov/pubmed/36081510
http://dx.doi.org/10.3389/fimmu.2022.943667