Novel topical esmolol hydrochloride improves wound healing in diabetes by inhibiting aldose reductase, generation of advanced glycation end products, and facilitating the migration of fibroblasts

AIMS/OBJECTIVES: Wound healing in people with diabetes is delayed secondary to impaired nitric oxide generation, advanced glycation end products (AGE), and poor migration of epithelial cells. We developed a novel topical esmolol hydrochloride (Galnobax) and assessed its efficacy for wound healing in...

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Detalles Bibliográficos
Autores principales: Kulkarni, Sudhir A., Deshpande, Supreet K., Rastogi, Ashu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446078/
https://www.ncbi.nlm.nih.gov/pubmed/36082077
http://dx.doi.org/10.3389/fendo.2022.926129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446078/
https://www.ncbi.nlm.nih.gov/pubmed/36082077
http://dx.doi.org/10.3389/fendo.2022.926129

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