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Novel topical esmolol hydrochloride improves wound healing in diabetes by inhibiting aldose reductase, generation of advanced glycation end products, and facilitating the migration of fibroblasts
AIMS/OBJECTIVES: Wound healing in people with diabetes is delayed secondary to impaired nitric oxide generation, advanced glycation end products (AGE), and poor migration of epithelial cells. We developed a novel topical esmolol hydrochloride (Galnobax) and assessed its efficacy for wound healing in...
Autores principales: | Kulkarni, Sudhir A., Deshpande, Supreet K., Rastogi, Ashu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446078/ https://www.ncbi.nlm.nih.gov/pubmed/36082077 http://dx.doi.org/10.3389/fendo.2022.926129 |
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