Correlation of functional and radioligand binding characteristics of GPER ligands confirming aldosterone as a GPER agonist

Aldosterone exerts some of its effects not by binding to mineralocorticoid receptors, but rather by acting via G protein‐coupled estrogen receptors (GPER). To determine if aldosterone binds directly to GPER, we studied the ability of aldosterone to compete for the binding of [(3)H] 2‐methoxyestradio...

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Detalles Bibliográficos
Autores principales: Ding, Qingming, Chorazyczewski, Jozef, Gros, Robert, Motulsky, Harvey J., Limbird, Lee E., Feldman, Ross D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446082/
https://www.ncbi.nlm.nih.gov/pubmed/36065843
http://dx.doi.org/10.1002/prp2.995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446082/
https://www.ncbi.nlm.nih.gov/pubmed/36065843
http://dx.doi.org/10.1002/prp2.995

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