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Correlation of functional and radioligand binding characteristics of GPER ligands confirming aldosterone as a GPER agonist
Aldosterone exerts some of its effects not by binding to mineralocorticoid receptors, but rather by acting via G protein‐coupled estrogen receptors (GPER). To determine if aldosterone binds directly to GPER, we studied the ability of aldosterone to compete for the binding of [(3)H] 2‐methoxyestradio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446082/ https://www.ncbi.nlm.nih.gov/pubmed/36065843 http://dx.doi.org/10.1002/prp2.995 |