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The prognostic potential of fragmented CK18 serum levels in HCC patients reflecting disease progression and overall hepatocyte damage

BACKGROUND: Fragmented cytokeratin 18 (fCK18) is released from damaged hepatocytes undergoing apoptosis and is recognized as a liver condition biomarker. We have developed a highly sensitive serum fCK18 CLEIA and reported that serum levels of this caspase-derived protein were significantly associate...

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Detalles Bibliográficos
Autores principales: Eguchi, Akiko, Iwasa, Motoh, Tamai, Yasuyuki, Yamada, Minori, Okuno, Koji, Shigefuku, Ryuta, Yoshikawa, Kyoko, Tempaku, Mina, Sakaguchi, Koji, Tanaka, Hideaki, Sugimoto, Kazushi, Kobayashi, Yoshinao, Yamaguchi, Tetsuji, Nakagawa, Hayato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446083/
https://www.ncbi.nlm.nih.gov/pubmed/36081568
http://dx.doi.org/10.3389/fonc.2022.993705