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The Hyperintense study: Assessing the effects of induced blood pressure increase and decrease on MRI markers of cerebral small vessel disease: Study rationale and protocol

BACKGROUND: Neuroimaging markers of cerebral small vessel disease (SVD) are common in older individuals, but the pathophysiological mechanisms causing these lesions remain poorly understood. Although hypertension is a major risk factor for SVD, the direct causal effects of increased blood pressure a...

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Detalles Bibliográficos
Autores principales: Janssen, Esther, ter Telgte, Annemieke, Verburgt, Esmée, de Jong, Joost JA, Marques, José P, Kessels, Roy PC, Backes, Walter H, Maas, Marnix C, Meijer, Frederick JA, Deinum, Jaap, Riksen, Niels P, Tuladhar, Anil M, de Leeuw, Frank-Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446329/
https://www.ncbi.nlm.nih.gov/pubmed/36082259
http://dx.doi.org/10.1177/23969873221100331