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Hypermethylation of tumor suppressor lncRNA MEF2C-AS1 frequently happened in patients at all stages of colorectal carcinogenesis

BACKGROUND: The novel long noncoding RNA MEF2C-AS1 has been identified to play suppressor roles during tumorigenesis. DNA methylation has a regulatory effect on gene expression in cancer initiation and progression. However, the methylation status of MEF2C-AS1 and its role in colorectal cancer (CRC)...

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Detalles Bibliográficos
Autores principales: Qian, Sangni, Lin, Shujuan, Xu, Xin, Bai, Hao, Yeerken, Aibuta, Ying, Xiaojiang, Li, Zhenjun, Fei, Xinglin, Yang, Jinhua, Tang, Mengling, Wang, Jianbing, Jin, Mingjuan, Chen, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446566/
https://www.ncbi.nlm.nih.gov/pubmed/36064442
http://dx.doi.org/10.1186/s13148-022-01328-1