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Chicken cathelicidin-2 promotes NLRP3 inflammasome activation in macrophages

Chicken cathelicidin-2 (CATH-2) as a host defense peptide has been identified to have potent antimicrobial and immunomodulatory activities. Here, we reported the mechanism by which CATH-2 modulates NLRP3 inflammasome activation. Our results show that CATH-2 and ATP as a positive control induced secr...

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Detalles Bibliográficos
Autores principales: Peng, Lianci, Tian, Hongliang, Lu, Yi, Jia, Kaixiang, Ran, Jinrong, Tao, Qi, Li, Gang, Wan, Chao, Ye, Chao, Veldhuizen, Edwin J. A., Chen, Hongwei, Fang, Rendong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446576/
https://www.ncbi.nlm.nih.gov/pubmed/36064470
http://dx.doi.org/10.1186/s13567-022-01083-4