11β-HSD1 participates in epileptogenesis and the associated cognitive impairment by inhibiting apoptosis in mice

BACKGROUND: Glucocorticoid signalling is closely related to both epilepsy and associated cognitive impairment, possibly through mechanisms involving neuronal apoptosis. As a critical enzyme for glucocorticoid action, the role of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) in epileptogenesis and as...

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Detalles Bibliográficos
Autores principales: Li, Xueying, Qiu, Wanhua, Deng, Lu, Lin, Jingjing, Huang, Wenting, Xu, Yuchen, Zhang, Mulan, Jones, Nigel C., Lin, Runxuan, Xu, Huiqin, Lin, Li, Li, Peijun, Wang, Xinshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446697/
https://www.ncbi.nlm.nih.gov/pubmed/36064418
http://dx.doi.org/10.1186/s12967-022-03618-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446697/
https://www.ncbi.nlm.nih.gov/pubmed/36064418
http://dx.doi.org/10.1186/s12967-022-03618-x

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