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Serum level of total histone 3, H3K4me3, and H3K27ac after non-emergent cardiac surgery suggests the persistence of smoldering inflammation at 3 months in an adult population

BACKGROUND: Despite clinical relevance of immunological activation due to histone leakage into the serum following cardiac surgery, long-term data describing their longitudinal dynamic are lacking. Therefore, this study examines the serum levels of histone 3 (tH3) and its modifications (H3K4me3 and...

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Detalles Bibliográficos
Autores principales: Laudanski, Krzysztof, Liu, Da, Hajj, Jihane, Ghani, Danyal, Szeto, Wilson Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446722/
https://www.ncbi.nlm.nih.gov/pubmed/36068552
http://dx.doi.org/10.1186/s13148-022-01331-6