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Serum level of total histone 3, H3K4me3, and H3K27ac after non-emergent cardiac surgery suggests the persistence of smoldering inflammation at 3 months in an adult population
BACKGROUND: Despite clinical relevance of immunological activation due to histone leakage into the serum following cardiac surgery, long-term data describing their longitudinal dynamic are lacking. Therefore, this study examines the serum levels of histone 3 (tH3) and its modifications (H3K4me3 and...
Autores principales: | Laudanski, Krzysztof, Liu, Da, Hajj, Jihane, Ghani, Danyal, Szeto, Wilson Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446722/ https://www.ncbi.nlm.nih.gov/pubmed/36068552 http://dx.doi.org/10.1186/s13148-022-01331-6 |
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