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Safety of beta-blocker and calcium channel blocker antihypertensive drugs in pregnancy: a Mendelian randomization study

BACKGROUND: Beta-blocker (BB) and calcium channel blocker (CCB) antihypertensive drugs are commonly used in pregnancy. However, data on their relative impact on maternal and foetal outcomes are limited. We leveraged genetic variants mimicking BB and CCB antihypertensive drugs to investigate their ef...

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Detalles Bibliográficos
Autores principales: Ardissino, Maddalena, Slob, Eric A. W., Rajasundaram, Skanda, Reddy, Rohin K., Woolf, Benjamin, Girling, Joanna, Johnson, Mark R., Ng, Fu Siong, Gill, Dipender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446737/
https://www.ncbi.nlm.nih.gov/pubmed/36064525
http://dx.doi.org/10.1186/s12916-022-02483-1