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Synovial membrane-derived mesenchymal progenitor cells from osteoarthritic joints in dogs possess lower chondrogenic-, and higher osteogenic capacity compared to normal joints

BACKGROUND: Synovial membrane-derived mesenchymal progenitor cells (SM-MPCs) are a promising candidate for the cell-based treatment of osteoarthritis (OA) considering their in vitro and in vivo capacity for cartilage repair. However, the OA environment may adversely impact their regenerative capacit...

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Detalles Bibliográficos
Autores principales: Teunissen, M., Ahrens, N. S., Snel, L., Narcisi, R., Kamali, S. A., van Osch, G. J. V. M., Meij, B. P., Mastbergen, S. C., Sivasubramaniyan, K., Tryfonidou, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446738/
https://www.ncbi.nlm.nih.gov/pubmed/36064441
http://dx.doi.org/10.1186/s13287-022-03144-z