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Purkinje cell vulnerability induced by diffuse traumatic brain injury is linked to disruption of long-range neuronal circuits

Cerebellar dysfunction is commonly observed following traumatic brain injury (TBI). While direct impact to the cerebellum by TBI is rare, cerebellar pathology may be caused by indirect injury via cortico-cerebellar pathways. To address the hypothesis that degeneration of Purkinje cells (PCs), which...

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Detalles Bibliográficos
Autores principales: Özen, Ilknur, Mai, Hongcheng, De Maio, Alessandro, Ruscher, Karsten, Michalettos, Georgios, Clausen, Fredrik, Gottschalk, Michael, Ansar, Saema, Arkan, Sertan, Erturk, Ali, Marklund, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446851/
https://www.ncbi.nlm.nih.gov/pubmed/36064443
http://dx.doi.org/10.1186/s40478-022-01435-3