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The cytokine IL-27 reduces inflammation and protects photoreceptors in a mouse model of retinal degeneration

BACKGROUND: Retinal degenerative diseases are a group of conditions characterized by photoreceptor death and vision loss. Excessive inflammation and microglial activation contribute to the pathology of retinal degenerations and a major focus in the field is identifying more effective anti-inflammato...

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Detalles Bibliográficos
Autores principales: Nortey, Andrea, Garces, Kimberly, Carmy-Bennun, Tal, Hackam, Abigail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446869/
https://www.ncbi.nlm.nih.gov/pubmed/36064575
http://dx.doi.org/10.1186/s12974-022-02576-x