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BTLA inhibition has a dominant role in the cis-complex of BTLA and HVEM

The engagement of the herpesvirus entry mediator (HVEM, TNFRSF14) by the B and T lymphocyte attenuator (BTLA) represents a unique interaction between an activating receptor of the TNFR-superfamily and an inhibitory receptor of the Ig-superfamily. BTLA and HVEM have both been implicated in the regula...

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Detalles Bibliográficos
Autores principales: Battin, Claire, Leitner, Judith, Waidhofer-Söllner, Petra, Grabmeier-Pfistershammer, Katharina, Olive, Daniel, Steinberger, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446882/
https://www.ncbi.nlm.nih.gov/pubmed/36081508
http://dx.doi.org/10.3389/fimmu.2022.956694