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Abstract 5 Human Umbilical Cord Blood-Derived Cell Therapy Product, DUOC-01, Promotes Remyelination by Driving the Differentiation of Oligodendrocyte Progenitor Cells

INTRODUCTION: DUOC-01 is a macrophage-like cell therapy product manufactured by culturing banked human umbilical cord blood cells under GMP conditions. Currently, the safety of DUOC-01 is being tested as a bridging therapy in children with demyelinating leukodystrophies undergoing unrelated donor um...

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Detalles Bibliográficos
Autores principales: Xu, Li, Saha, Arjun, Parrott, Roberta, O’Neil, Shane, Kurtzberg, Joanne, Filiano, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9446916/
http://dx.doi.org/10.1093/stcltm/szac057.005