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Silencing of hypothalamic FGF11 prevents diet-induced obesity

Fibroblast growth factor 11 (FGF11) is a member of the intracellular fibroblast growth factor family. Here, we report the central role of FGF11 in the regulation of metabolism. Lentiviral injection of Fgf11 shRNA into the arcuate nucleus of the mouse hypothalamus decreased weight gain and fat mass,...

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Detalles Bibliográficos
Autores principales: Cho, Jae Hyun, Kim, Kyungchan, Cho, Han Chae, Lee, Jaemeun, Kim, Eun-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447329/
https://www.ncbi.nlm.nih.gov/pubmed/36064426
http://dx.doi.org/10.1186/s13041-022-00962-3