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RNA G-quadruplex formed in SARS-CoV-2 used for COVID-19 treatment in animal models

The ongoing COVID-19 pandemic has continued to affect millions of lives worldwide, leading to the urgent need for novel therapeutic strategies. G-quadruplexes (G4s) have been demonstrated to regulate life cycle of multiple viruses. Here, we identify several highly conservative and stable G4s in SARS...

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Detalles Bibliográficos
Autores principales: Qin, Geng, Zhao, Chuanqi, Liu, Yan, Zhang, Cheng, Yang, Guang, Yang, Jie, Wang, Zhao, Wang, Chunyu, Tu, Changchun, Guo, Zhendong, Ren, Jinsong, Qu, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447362/
https://www.ncbi.nlm.nih.gov/pubmed/36068208
http://dx.doi.org/10.1038/s41421-022-00450-x