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Hyaluronic acid restored protein permeability across injured human lung microvascular endothelial cells

Lung endothelial permeability is a key pathological feature of acute respiratory distress syndrome. Hyaluronic acid (HA), a major component of the glycocalyx layer on the endothelium, is generated by HA synthase (HAS) during inflammation and injury and is critical for repair. We hypothesized that ad...

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Detalles Bibliográficos
Autores principales: Sugita, Shinji, Naito, Yoshifumi, Zhou, Li, He, Hongli, Hao, Qi, Sakamoto, Atsuhiro, Lee, Jae W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447422/
https://www.ncbi.nlm.nih.gov/pubmed/36089980
http://dx.doi.org/10.1096/fba.2022-00006