Intranasal administration of abatacept enhances IL-35(+) and IL-10(+) producing Bregs in lung tissues of ovalbumin-sensitized asthmatic mice model

BACKGROUNDS: Treating asthmatic rheumatoid arthritis patients with abatacept has been shown to associate with better control of asthma symptoms. However, the mechanism behind that is not investigated. METHODS: Ovalbumin (OVA)- sensitized BALB/c female mice were treated intranasally (IN) or intraperi...

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Detalles Bibliográficos
Autores principales: Alenazy, Maha Fahad, Sharif-Askari, Fatemeh Saheb, El-Wetidy, Mohammed S., Sharif-Askari, Narjes Saheb, Hachim, Ibrahim Yaseen, Temsah, Mohammad-Hani, Saddik, Basema, Al-Kufaidy, Roua, Omair, Maha A., Alshawakir, Yasser A., Fathaddin, Amany Adulgadel, Hannawi, Suad, Hamid, Qutayba, Omair, Mohammed A., Al-Muhsen, Saleh, Halwani, Rabih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447931/
https://www.ncbi.nlm.nih.gov/pubmed/36067164
http://dx.doi.org/10.1371/journal.pone.0271689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9447931/
https://www.ncbi.nlm.nih.gov/pubmed/36067164
http://dx.doi.org/10.1371/journal.pone.0271689

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