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Ischemic damage to every segment of the oxidative phosphorylation cascade elevates ETC driving force and ROS production in cardiac mitochondria
Myocardial ischemia has long-lasting negative impacts on cardiomyocyte mitochondrial ATP production. However, the location(s) of damage to the oxidative phosphorylation pathway responsible for altered mitochondrial function is unclear. Mitochondrial reactive oxygen species (ROS) production increases...
Autores principales: | Kuzmiak-Glancy, Sarah, Glancy, Brian, Kay, Matthew W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448280/ https://www.ncbi.nlm.nih.gov/pubmed/35867709 http://dx.doi.org/10.1152/ajpheart.00129.2022 |
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