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GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base

The gap junction complex functions as a transport channel across the membrane. Among gap junction subunits, gap junction protein α1 (GJA1) is the most commonly expressed subunit. A recent study showed that GJA1 is necessary for the maintenance of motile cilia; however, the molecular mechanism and fu...

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Detalles Bibliográficos
Autores principales: Jang, Dong Gil, Kwon, Keun Yeong, Kweon, Yeong Cheon, Kim, Byung-gyu, Myung, Kyungjae, Lee, Hyun-Shik, Young Park, Chan, Kwon, Taejoon, Park, Tae Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448326/
https://www.ncbi.nlm.nih.gov/pubmed/36004726
http://dx.doi.org/10.7554/eLife.81016