Cargando…

Synthesis and biological activity evaluation of 3-(hetero) arylideneindolin-2-ones as potential c-Src inhibitors

Inhibition of c-Src is considered one of the most studied approaches to cancer treatment, with several heterocyclic compounds approved during the last 15 years as chemotherapeutic agents. Starting from the biological evaluation of an in-house collection of small molecules, indolinone was selected as...

Descripción completa

Detalles Bibliográficos
Autores principales: Princiotto, Salvatore, Musso, Loana, Manetti, Fabrizio, Marcellini, Valentina, Maga, Giovanni, Crespan, Emmanuele, Perini, Cecilia, Zaffaroni, Nadia, Beretta, Giovanni Luca, Dallavalle, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448371/
https://www.ncbi.nlm.nih.gov/pubmed/36050846
http://dx.doi.org/10.1080/14756366.2022.2117317