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Synthesis and biological activity evaluation of 3-(hetero) arylideneindolin-2-ones as potential c-Src inhibitors
Inhibition of c-Src is considered one of the most studied approaches to cancer treatment, with several heterocyclic compounds approved during the last 15 years as chemotherapeutic agents. Starting from the biological evaluation of an in-house collection of small molecules, indolinone was selected as...
Autores principales: | Princiotto, Salvatore, Musso, Loana, Manetti, Fabrizio, Marcellini, Valentina, Maga, Giovanni, Crespan, Emmanuele, Perini, Cecilia, Zaffaroni, Nadia, Beretta, Giovanni Luca, Dallavalle, Sabrina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448371/ https://www.ncbi.nlm.nih.gov/pubmed/36050846 http://dx.doi.org/10.1080/14756366.2022.2117317 |
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