Enhanced oral absorption of insulin: hydrophobic ion pairing and a self-microemulsifying drug delivery system using a D-optimal mixture design

The lipophilicity of a peptide drug can be considerably increased by hydrophobic ion pairing with amphiphilic counterions for successful incorporation into lipid-based formulations. Herein, to enhance the oral absorption of insulin (INS), a self-microemulsifying drug delivery system (SMEDDS) formula...

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Detalles Bibliográficos
Autores principales: Goo, Yoon Tae, Lee, Sangkil, Choi, Ji Yeh, Kim, Min Song, Sin, Gi Hyeong, Hong, Sun Ho, Kim, Chang Hyun, Song, Seh Hyon, Choi, Young Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448375/
https://www.ncbi.nlm.nih.gov/pubmed/36050870
http://dx.doi.org/10.1080/10717544.2022.2118399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448375/
https://www.ncbi.nlm.nih.gov/pubmed/36050870
http://dx.doi.org/10.1080/10717544.2022.2118399

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