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Discovery of novel conjugates of quinoline and thiazolidinone urea as potential anti-colorectal cancer agent
Based on the obtained SARs, further structural optimisation of compound BC2021-104511-15i was conducted in this investigation, and totally ten novel quinoline derivates were designed, synthesised and optimised for biological activity. Among them, compound 10a displayed significant in vitro anticance...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448386/ https://www.ncbi.nlm.nih.gov/pubmed/36043496 http://dx.doi.org/10.1080/14756366.2022.2117318 |