Enhancement of the oral bioavailability of isopropoxy benzene guanidine though complexation with hydroxypropyl-β-cyclodextrin

Isopropoxy benzene guanidine (IBG) is a novel substituted benzene guanidine analogue with antibacterial activity against multidrug-resistant bacteria. However, the bioavailability of IBG is not optimal due to its finite aqueous solubility, thus hampering its potential therapeutic exploitation. In th...

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Detalles Bibliográficos
Autores principales: Lu, Yixing, Yang, Liuye, Zhang, Wanying, Xie, Shiting, Zhao, Feifei, Peng, Xianfeng, Qin, Zonghua, Zeng, Dongping, Zeng, Zhenling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448396/
https://www.ncbi.nlm.nih.gov/pubmed/36062487
http://dx.doi.org/10.1080/10717544.2022.2118400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448396/
https://www.ncbi.nlm.nih.gov/pubmed/36062487
http://dx.doi.org/10.1080/10717544.2022.2118400

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