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Chlorogenic acid promotes angiogenesis and attenuates apoptosis following cerebral ischaemia-reperfusion injury by regulating the PI3K-Akt signalling

CONTEXT: Chlorogenic acid (CGA) has good antioxidant effects, but its explicit mechanism in cerebral ischaemia-reperfusion injury is still uncertain. OBJECTIVE: We studied the effect of CGA in human brain microvascular endothelial cells (HBMECs) under OGD/R damage. MATERIALS AND METHODS: HBMECs in 4...

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Detalles Bibliográficos
Autores principales: Fan, Yong, Li, Yongkun, Yang, Yongkai, Lin, Kunzhe, Lin, Qingqiang, Luo, Shenghui, Zhou, Xiaohui, Lin, Qun, Zhang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448406/
https://www.ncbi.nlm.nih.gov/pubmed/35981220
http://dx.doi.org/10.1080/13880209.2022.2110599