Fabrication of nanostructured lipid carriers ocugel for enhancing Loratadine used in treatment of COVID-19 related symptoms: statistical optimization, in-vitro, ex-vivo, and in-vivo studies evaluation

Loratadine (LORA), is a topical antihistamine utilized in the treatment of ocular symptoms of COVID-19. The study aimed to develop a Loratadine Nanostructured Lipid Carriers Ocugel (LORA-NLCs Ocugel), enhance its solubility, trans-corneal penetrability, and bioavailability. full-factorial design was...

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Detalles Bibliográficos
Autores principales: Abdelmonem, Rehab, Al-Samadi, Inas Essam Ibrahim, El Nashar, Rasha M., Jasti, Bhaskara R., El-Nabarawi, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448409/
https://www.ncbi.nlm.nih.gov/pubmed/36065090
http://dx.doi.org/10.1080/10717544.2022.2115164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448409/
https://www.ncbi.nlm.nih.gov/pubmed/36065090
http://dx.doi.org/10.1080/10717544.2022.2115164

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