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Trametenolic Acid Ameliorates the Progression of Diabetic Nephropathy in db/db Mice via Nrf2/HO-1 and NF-κB-Mediated Pathways

Diabetic nephropathy (DN) is a fatal complication of diabetes and the main cause of end-stage renal disease. Due to the suboptimal effects of current treatments, there is an urgent need to develop new therapeutic strategies for DN. Trametenolic acid (TA), a lanostane-type tetracyclic triterpenoid, i...

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Detalles Bibliográficos
Autores principales: Duan, Qi, Tian, Lingling, Feng, Jiabing, Ping, Xinbo, Li, Lihong, Yaigoub, Hasnaa, Li, Rongshan, Li, Yafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448586/
https://www.ncbi.nlm.nih.gov/pubmed/36081452
http://dx.doi.org/10.1155/2022/6151847